The four good-for-nothing jokers from Dhamaal - Roy (Riteish Deshmukh), Manav (Jaaved Jaafery) Adi (Arshad Warsi) and Boman (Ashish Chowdhry) are back again! They are still as stupid and useless as before. Hard work is a strict no no and the only work they have ever done in their lives is to lie down on their backsides and dream about a good life where they have everything without doing anything! And then suddenly they see their old arch enemy - the corrupt Inspector Kabir (Sanjay Dutt). But he's no longer a cop and instead of chasing crooks, he's chasing money - driving a Merc and has a posh office and a lavish villa. The four madcaps are green with envy and decide that come what may, by hook or by crook they will share Kabir's good fortune. And so they blackmail Kabir into making them his business partners. They are in seventh heaven, yippee, all their dreams are coming true. What they don't know is that soon their dreams are going to turn into nightmares because Kabir has his own hidden agenda, only shared by his sultry wife Kamini (Mallika Sherawat) and lovely sister Kiya (Kangna Ranaut).
And so starts a game of one-up-manship, with both sides having tricks up their sleeves and where sundry characters like bhai turned sadhu - Batabhai (Satish Kaushik) and King of Casinos Johnny Bonzola, turn up to make the foursome's life miserable.
And of course there's a helluva lot of money at stake. There are also lots of twists and turns and a bellyful of laughs. But who will have the last laugh? Canny Kabir or our four loveable jokers?